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第173回WPI-IIISセミナーのお知らせ / Announcement of the 173rd WPI-IIIS Seminar (This seminar will be held in English)

Dear Colleagues,

We are going to have the 173rd WPI-IIIS Seminar on-site/on-line as follows.

Date: Wednesday, November 30, 2022
Time: 11:00 -12:30
Venue:  Join us online via Teams
*To register, please visit the URL below: Teams information will be sent to registered participants. (Deadline: November 29th)
https://forms.gle/ncQf2tm1RDcT8RpG8

Speaker:   Dr. Joseph Bass
Division of Endocrinology, Metabolism and Molecular, Northwestern University

Subject: “Homeostasis in Sleep, Feeding and Thermogenesis”

Summary:  Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity. Conversely, restricting feeding to the active period mitigates metabolic syndrome through mechanisms that remain unknown. Genetic enhancement of adipocyte thermogenesis through ablation of the zinc finger protein 423 attenuates obesity caused by consumption of a high-fat diet during the sleep phase by increasing futile creatine cycling. Circadian control of adipocyte creatine metabolism aligns thermogenesis with the light/dark cycle, and genetic enhancement of adipocyte circadian rhythms ameliorates obesity. Our findings reveal homeostatic mechanisms linking sleep and metabolism.

Click here to access our website: https://wpi-iiis.tsukuba.ac.jp/event/seminar/

Contact: International Institute for Integrative Sleep Medicine
Phone: 029-853-5857 (ext. 5857)

Yours sincerely,

Masashi Yanagisawa,
WPI – International Institute for Integrative Sleep Medicine, University of Tsukuba

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セミナー開催についてのお知らせ

第173回WPI-IIISセミナーを以下のとおりオンサイトとオンラインで行いますので、皆様ぜひご参加ください。

日時:2022年11月30日(水) 11:00 -12:30
会場:Teamsによるオンラインセミナー
*以下のURLにアクセスして参加登録をお願いします。参加登録をいただいた方には、別途Teams情報をお送りいたします。(登録〆切11月29日)
https://forms.gle/ncQf2tm1RDcT8RpG8

演者: Dr. Joseph Bass
Division of Endocrinology, Metabolism and Molecular, Northwestern University

演題 : “Homeostasis in Sleep, Feeding and Thermogenesis”

要旨 :  Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity. Conversely, restricting feeding to the active period mitigates metabolic syndrome through mechanisms that remain unknown. Genetic enhancement of adipocyte thermogenesis through ablation of the zinc finger protein 423 attenuates obesity caused by consumption of a high-fat diet during the sleep phase by increasing futile creatine cycling. Circadian control of adipocyte creatine metabolism aligns thermogenesis with the light/dark cycle, and genetic enhancement of adipocyte circadian rhythms ameliorates obesity. Our findings reveal homeostatic mechanisms linking sleep and metabolism.

HPへのアクセスはこちらから:https://wpi-iiis.tsukuba.ac.jp/japanese/event/seminar/

筑波大学国際統合睡眠医科学研究機構
機構長 柳沢 正史

問い合わせ:国際統合睡眠医科学研究機構 (内線5857)