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第172回WPI-IIISセミナーのお知らせ Announcement of the 172nd WPI-IIIS Seminar (This seminar will be held in English)

Dear Colleagues,

We are going to have the 172nd WPI-IIIS Seminar online as follows.

Date: Wednesday, November 2, 2022
Time: 11:00 -12:00
Venue: Join us online via Teams
*To register, please visit the URL below.
https://forms.gle/j6wXGKireSbDJdjd9 Teams information will be sent to registered participants. (Deadline: November 1st)

Speaker: Dr. Paul Frankland
Hospital for Sick Children, Toronto, CANADA

Subject: “Hippocampal engrams”

Summary: Learning is thought to strengthen the connections between co-activated neurons, leading to the formation of a neuronal ensemble (or ‘engram’) corresponding to a specific memory. Using immediate early gene (IEG)-based methods to tag manipulate engrams, I will present two unpublished stories. The first story asks whether the nature of engrams changes across development, and I will show how age-dependent increases in engram sparsity are responsible for age-dependent increases in memory precision. The second story asks how experience modifies existing engrams. Specifically, we have found that extinction recruits microglia to engram cells leading to complement-dependent remodeling of engram cell connectivity.

Click here for more information: http://wpi-iiis.tsukuba.ac.jp/seminar Contact: International Institute for Integrative Sleep Medicine
Phone: 029-853-5857 (ext. 5857)

Yours sincerely,

Masashi Yanagisawa,
WPI – International Institute for Integrative Sleep Medicine, University of Tsukuba

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セミナー開催についてのお知らせ

第172回WPI-IIISセミナーを以下のとおりオンラインで行いますので、皆様ぜひご参加ください。

日時:2022年11月2日(水) 11:00 -12:00
会場: Teamsによるオンラインセミナー
*以下のURLにアクセスして参加登録をお願いします。参加登録をいただいた方には、別途Teams情報をお送りいたします。(登録〆切11月1日)
https://forms.gle/j6wXGKireSbDJdjd9

演者 : Dr. Paul Frankland
Hospital for Sick Children, Toronto, CANADA

演題 : “Hippocampal engrams”

要旨 : Learning is thought to strengthen the connections between co-activated neurons, leading to the formation of a neuronal ensemble (or ‘engram’) corresponding to a specific memory. Using immediate early gene (IEG)-based methods to tag manipulate engrams, I will present two unpublished stories. The first story asks whether the nature of engrams changes across development, and I will show how age-dependent increases in engram sparsity are responsible for age-dependent increases in memory precision. The second story asks how experience modifies existing engrams. Specifically, we have found that extinction recruits microglia to engram cells leading to complement-dependent remodeling of engram cell connectivity.

詳細はこちらからもご覧になれます:http://wpi-iiis.tsukuba.ac.jp/japanese/seminar

筑波大学国際統合睡眠医科学研究機構
機構長 柳沢 正史

問 い合わせ:国際統合睡眠医科学研究機構 (内線5857)